Karen Pendergrass, Standards Team

Fecal Bacteroides and Enterocloster predicted fibrous stenosis in Crohn's disease, while Streptococcus and related taxa predicted non-stenosis.

Seasonal gut microbiota shifts toward Firmicutes enrichment enhance lipid metabolism across four Ursidae species, challenging the idea that giant panda metabolic regulation is unique.

In 588 community-dwelling 27-year-olds, severe steatotic liver disease was tied to lower gut microbial diversity and depletion of butyrate-producing bacteria such as Coprococcus, Faecalibacterium, and Odoribacter. The pattern resembles other chronic inflammatory conditions, pointing to early microbiome changes before advanced liver disease.

Gut microbiota shifts in APP/PS1 mice, including rises in Escherichia-Shigella and Desulfovibrio, precede cerebral amyloid plaques and microglial activation.

A three-generation, multi-omics study of 200 family members found infant gut microbiota are less diverse and metabolically distinct from mothers and grandmothers.

Skin bacterial diversity fell sharply in intensive care patients with severe pneumonia, and skin genera including Staphylococcus, Acinetobacter, and Stenotrophomonas overlapped with pathogens cultured from their airways.

In infertile couples, genital microbiota were niche-specific: female sites were dominated by Lactobacillus while male samples showed greater diversity, including bacteria linked to bacterial vaginosis. Only limited evidence of microbiota transmission between partners was found.

In a human birth cohort, neonates whose mothers ate a high-fat diet in pregnancy had a distinct gut microbiome at birth, with a notable depletion of Bacteroides that persisted to 4 to 6 weeks of age, independent of maternal obesity.

In 132 people including 90 with atopic dermatitis, a subspecies-level shift within Faecalibacterium prausnitzii was strongly linked to the disease. It reduced high butyrate and propionate producers, lowering fecal butyrate and propionate and suggesting a weakened gut barrier.

Children with food sensitization had lower overall gut microbial diversity and fewer Bacteroidetes, with more Firmicutes. Increased Clostridium IV and Subdoligranulum and decreased Bacteroides and Veillonella best distinguished sensitized children from healthy controls.

In this Chinese cohort, gut bacteria shifted as tuberculosis progressed from latent to active disease. Probiotic genera like Romboutsia, Bifidobacterium and Lactobacillus marked latent infection, while pro-inflammatory Ruminococcus gnavus, Streptococcus and Erysipelatoclostridium rose in active tuberculosis.

In 200 fecal samples from newborns in the MAMI cohort, a lower gut abundance of Bifidobacterium at 7 days and 1 month of age tracked with a higher load of antibiotic resistance genes, while breastfeeding and vaginal birth favored Bifidobacterium dominance.

Only the study title was available, and it indicates dietary factors shape the human gut microbiota at both the species and within-species strain genetic level.

Neonates exposed to but uninfected by HIV show altered gut bacteria and virome, with breast milk IgA from HIV-positive mothers less able to curb Blautia coccoides growth, linked to inflammation.

Found a modified Mediterranean-ketogenic diet raised gut propionate and butyrate while shifting microbiota linked to Alzheimer's CSF biomarkers.

Patients with generalized anxiety disorder show reduced gut microbial diversity and SCFA-producing bacteria alongside overgrowth of Escherichia-Shigella, Fusobacterium, and Ruminococcus gnavus, a dysbiosis that persisted even after remission.

Sequencing cervical mucus from 30 women with endometriosis and 39 without, researchers found Enterobacteriaceae and Streptococcus significantly more abundant in the endometriosis group by real-time PCR, alongside increased Corynebacterium, Flavobacterium, and Pseudomonas.

Obese and normal-weight adults did not differ in the Firmicutes-to-Bacteroidetes ratio. Instead, obesity was defined by specific taxa and higher fecal short-chain fatty acids: total SCFAs reached 214 mM in obese versus 120 mM in normal-weight individuals, with acetate and butyrate significantly elevated.

Parkinson's disease and Parkinson's disease medications each leave distinct, independent signatures on the gut microbiome after controlling for dozens of confounders.

In a matched cohort study, AML patients showed gut microbiome shifts, with lower Eubacterium eligens correlating with muscle weakness and reduced citrulline.

Four next-generation probiotic Faecalibacterium prausnitzii strains isolated from healthy donors reduced liver damage in a high-fructose high-fat diet mouse model of NASH.

Using full-length 16S sequencing of saliva, pituitary adenoma patients showed greater salivary microbial diversity than healthy people. Each of four tumor phenotypes carried unique genera, and single genera distinguished the ACTH, GH, and PRL subtypes with AUC values of 0.91 to 0.93.

Depleted Bacteroides and Alistipes species correlated with higher inflammatory biomarkers in people with HIV, linking gut microbiota shifts to cardiovascular risk.

A Chinese pilot study links gut microbiota composition to asthenozoospermia, pointing to gut-testis axis disruption as a factor in reduced sperm motility.