Karen Pendergrass, Standards Team

The study reviewed the effectiveness of partially hydrolyzed guar gum (PHGG), a water-soluble prebiotic dietary fiber, on cognitive function, sleep efficiency, and overall mental health in elderly individuals. The research specifically focused on assessing the impact of PHGG supplementation on cognitive domains such as visual memory and simple attention, sleep quality parameters […]

The study links lead and cadmium exposure to increased endometriosis risk, emphasizing lead’s role at low blood levels and synergistic effects with cadmium. It advocates for strict monitoring and preventive measures to minimize exposure.

The study focused on the potential impact of environmental exposure to dioxin-like polychlorinated biphenyls (PCBs) on the development of endometriosis. It specifically reviewed the complexities and challenges of determining the effects of such toxicants on human health, with an emphasis on reproductive tract diseases. Who was studied? The research predominantly referenced […]

The research focused on examining the effects of PCB 126, a dioxin-like pollutant, on gut health and microbiota as well as metabolic homeostasis in a mouse model predisposed to cardiometabolic diseases. The study investigated how exposure to this pollutant influences the gut microbiome, intestinal and systemic inflammation, metabolic hormones, and the development […]

This review highlights microbiome alterations in endometriosis, including gut and vaginal dysbiosis, and explores microbiome-targeted therapies and diagnostics.

The review focused on the safety and medical applications of clinoptilolite, a naturally occurring zeolite, for in vivo use. The analysis encompassed the physical and chemical properties of clinoptilolite, its detoxifying capabilities, and its potential therapeutic effects in both human and veterinary medicine. The review also considered various studies on clinoptilolite’s role […]

The study investigated the role of copper in microbial pathogenesis. Specifically, it examined how copper serves as both a necessary nutrient for microbial organisms and a microbial weapon used by hosts against pathogens. The research explored copper’s dual roles, its involvement in various microbial resistance mechanisms, and its interaction with the host’s […]

This study explores the mammary microbiota’s composition and function before and after breast cancer diagnosis, revealing dysbiosis and metabolic shifts as early markers.

The study focused on exploring the associations between the microbiota of the vaginal, cervical, and gut regions and stage 3–4 endometriosis in women. This research aimed to uncover potential differences in the microbiome composition between women diagnosed with advanced endometriosis and healthy controls, particularly at the genus level of microbial classification. […]

This study investigated the taxonomic and functional gut microbiota profiles of euthyroid individuals with and without thyroid peroxidase antibodies (TPOAb), a marker for autoimmune thyroid diseases such as Hashimoto’s thyroiditis. The goal was to assess whether gut microbiota composition differs in individuals with TPOAb before the clinical onset of autoimmune thyroid disease […]

The retrospective study explored the prevalence of endometriosis in patients with uterine malformations. It specifically investigated the relationship between different types of uterine malformations (obstructive, non-obstructive, and various classifications under the American Fertility Society (AFS)) and the incidence of endometriosis, which is characterized by the presence of endometrial tissue outside the uterus. The […]

The study investigated the differences in gut microbiota between men with erectile dysfunction (ED) and healthy controls to identify key microbiota associated with ED and explore the potential pathogenic role of specific bacteria. Who was studied? A total of 43 men diagnosed with ED and 16 healthy controls, all of whom met […]

The study investigated the causal effects of gut microbiota on scoliosis using a bidirectional two-sample Mendelian randomization (MR) approach. Specifically, it aimed to determine whether variations in the composition of gut microbiome taxa could influence the risk of developing scoliosis. The study utilized genetic variants as instrumental variables (IVs) from a large genome-wide […]

The study utilized a two-sample Mendelian randomization (MR) approach to assess the causal effects of gut microbiota on the risk of erectile dysfunction (ED). It analyzed the associations between specific gut microbiota and ED using genome-wide association study (GWAS) data. Who was studied? The study analyzed genetic and microbiota data from large […]

This study identifies gut dysbiosis in breast cancer patients, highlighting reduced SCFA-producing bacteria and altered microbial pathways. Findings suggest microbiome-targeted interventions could aid breast cancer treatment.

This review explores bacterial iron homeostasis, focusing on detoxification pathways, oxidative stress mitigation, and iron-storage mechanisms. It highlights regulatory proteins like Fur and DtxR and storage proteins like ferritins. These insights provide potential therapeutic targets for limiting bacterial growth and addressing iron-related dysbiosis in host-pathogen interactions.

The study focused on the association between the composition of cervical microbiota and pregnancy outcomes in a subfertile population undergoing in vitro fertilization (IVF). Specifically, it aimed to characterize the cervical microbiota of patients undergoing embryo transfer (ET) and assess whether the composition of these microbiota is associated with the outcomes of […]

This study links reduced gut microbial diversity and specific taxa (e.g., Acidaminococcus, Hungatella) to breast cancer, influenced by diet. Findings suggest microbiome-targeted interventions and dietary strategies could mitigate breast cancer risk.

Endometriosis significantly increases the risk of clear-cell, low-grade serous, and endometrioid ovarian cancers. This study highlights the need for subtype-specific ovarian cancer surveillance and prevention strategies.

The study investigated the association between calcium-phosphorus balance and adolescent idiopathic scoliosis (AIS) through a systematic review and meta-analysis of case-control and cross-sectional studies. Who was studied? The meta-analysis included a total of 646 AIS cases and 791 controls, comprising adolescents from various countries, with a focus on sex and menstruation […]

The study assessed thyroid function and oxidative stress in foundry workers occupationally exposed to lead (Pb) dust and fumes. It investigated the correlation between blood lead levels (BLL) and thyroid hormones, as well as markers of oxidative stress. Who was studied? The study involved 59 adult male foundry workers exposed to lead […]

The study investigated the antimicrobial, probiotic, and immunobiological effects of the Henola Cannabis sativae extract and its combinations with specific carriers: polyvinyl caprolactam-polyvinyl acetate-polyethylene glycol graft copolymer, magnesium aluminometasilicate, and hydroxypropyl-β-cyclodextrin. The study demonstrated that Henola Cannabis sativae extract, particularly when combined with carriers like hydroxypropyl-β-cyclodextrin, exhibits strong antimicrobial activity against various […]

This study examined the impact of heavy metal exposure on the prevalence and differentiation of osteoarthritis (OA) and rheumatoid arthritis (RA) using interpretable machine learning models. Researchers analyzed data from the National Health and Nutrition Examination Survey (NHANES) (2003–2020) to assess how various heavy metals contribute to arthritis risk. Who Was Studied? […]

This review emphasizes the significant alterations in gut microbiota in severe chronic heart failure (CHF) patients and suggests that gut microbiota modulation could be a promising avenue for therapeutic intervention. The study provides a foundation for future research aimed at leveraging gut microbiota to improve CHF management and patient health.