Divine Aleru, Microbiome Medicine Research Coordinator

This study examines the role of flagella in Listeria monocytogenes invasion, concluding that motility, not adhesion, is crucial for host cell invasion and early colonization.

This study explores Listeria monocytogenes contamination in poultry products, highlighting serotype distribution, antimicrobial resistance, and molecular subtyping methods used to track outbreaks and assess food safety.

This review discusses the genetic mechanisms behind Listeria monocytogenes resistance to LAB-produced bacteriocins, emphasizing receptor modifications and cross-resistance, and suggests strategies to counteract these challenges in food preservation.

This review explains how Listeria monocytogenes triggers and then evades macrophage autophagy, including SLAP formation that supports slow intracellular persistence.

This review explores the mechanisms of heavy metal resistance in Listeria monocytogenes, focusing on arsenic and cadmium resistance genes and their potential role in persistence and virulence in food and clinical settings.

This study analyzes antimicrobial resistance in Listeria monocytogenes isolates from clinical and food environments in France, highlighting the low prevalence of acquired resistance and the continued effectiveness of first-line treatments.

This study analyzes antimicrobial resistance in Listeria monocytogenes isolates from 2010 to 2021, finding no significant increase in resistance and highlighting key AMR genes.

This review discusses the rising antimicrobial resistance in Listeria species, focusing on their resistance mechanisms to antibiotics, biocides, and heavy metals, and their implications for food safety and public health.

This study explores the persistence of Listeria monocytogenes biofilms in food industries, stressing the need for stronger hygiene protocols to prevent contamination. It highlights genetic factors that contribute to biofilm formation and resistance.

The review examines the persistence of Listeria monocytogenes biofilms in the food industry and evaluates current cleaning methods, offering insights into innovative control strategies.

This study examines pregnancy-associated listeriosis in England and Wales, exploring factors influencing pregnancy outcomes and infant survival, with a focus on maternal symptoms and timing of infection.

The paper reviews Listeria monocytogenes, its global prevalence, risk factors, and clinical management of listeriosis, with a focus on vulnerable populations.

Manganese plays a pivotal role in microbial pathogenesis. As a vital cofactor for enzymes involved in antioxidant defense and metabolism, manganese is essential for pathogens, enabling them to survive within the host. However, when not properly managed, manganese can become toxic to both the host and the pathogen. The host’s immune system, through mechanisms like the secretion of calprotectin, tries to limit microbial access to manganese, creating an ongoing battle between host defenses and microbial survival .

This study examines the relationship between the metal content of human milk and the infant gut microbiota, highlighting metal-induced microbial shifts and their potential impact on infant health and development.

This study investigates the buffer capacity and systems of human whole saliva, revealing the key role of bicarbonate, saliva flow rate, and pH in maintaining oral health. It provides insights into the implications for dental health and saliva analysis.

This study addresses diagnostic challenges for manganese imbalances, providing algorithms for identifying hypermanganesemia and hypomanganesemia, and offering solutions to improve clinical diagnosis, including sample handling and reference range standardization.

This study optimizes electrothermal atomic absorption spectrometry (ETAAS) for detecting manganese in urine and blood samples, demonstrating high sensitivity and precision, and providing insights into the use of chemical modifiers for improved analysis.

This study explores how heavy metals in an ecological restoration area of a manganese mining site promote the diffusion of high-risk antibiotic resistance genes and pathogens through a transmission chain involving mulberry leaves, silkworms, and soil, raising concerns for public health and environmental safety.

This review explores how environmental bacteria acquire co-resistance to heavy metals and antibiotics, revealing complex genetic interactions and co-selection mechanisms.

This study links placental manganese levels, maternal gut microbiota, and preeclampsia risk, highlighting specific bacterial genera and metabolic pathways involved. It suggests that manganese may help mitigate preeclampsia, offering new insights for therapeutic strategies targeting the gut microbiome.

This study shows that manganese exposure triggers neuroinflammation in rats through the NLRP3 inflammasome, but fecal microbiota transplantation can alleviate these effects, suggesting microbiome-based therapies for neurotoxic and neurodegenerative diseases.

This study shows that fecal microbiome transplantation (FMT) can attenuate manganese-induced neurotoxicity by regulating the apelin signaling pathway and autophagy in the brain, offering new therapeutic insights into managing metal-induced neurodegenerative diseases.

This study shows how manganese exposure alters the gut microbiome and metabolic functions in a sex-specific manner in C57BL/6 mice. It highlights changes in neurotransmitter pathways and microbial composition that could impact brain health and suggests the need for sex-specific approaches to understanding metal toxicity.

This study identifies the MntABC manganese transporter as crucial for S. aureus survival after phagocytosis. It helps bacteria recover from oxidative stress by facilitating DNA repair through the NrdEF complex, offering new therapeutic targets to disrupt metal acquisition and combat bacterial infections.