Divine Aleru, Microbiome Medicine Research Coordinator

Three-month probiotic supplementation improved mental health and reduced NSAID reliance in women with primary dysmenorrhea, though it did not alter inflammatory cytokines or directly measure microbiome changes.

This study links a snack‐heavy dietary pattern to a significantly higher risk of moderate to severe dysmenorrhea among young women, highlighting the importance of dietary counseling in menstrual pain management.

This study links specific elements of the Mediterranean diet, particularly fruit and olive oil intake, to menstrual pain and characteristics, highlighting potential roles for anti-inflammatory foods in menstrual health among Spanish university women.

Zinc supplementation significantly reduces pain severity in women with primary dysmenorrhea, especially with longer durations of use, offering a safe and effective treatment option.

This meta-analysis demonstrates that cigarette smoking increases the risk of dysmenorrhea, with both current and former smokers showing a significantly higher likelihood of experiencing menstrual pain. Smoking cessation could be an effective intervention to alleviate symptoms.

This study identifies a strong association between concurrent tobacco smoking and alcohol drinking and increased dysmenorrhea risk. It emphasizes the need for lifestyle modifications, such as smoking cessation and exercise, to reduce menstrual pain.

This systematic review highlights elevated oxidative stress and potential antioxidant deficiencies in women with primary dysmenorrhea. While oxidative markers such as MDA and NO were significantly higher, the evidence on antioxidant status remains inconclusive, suggesting a need for further research into therapeutic interventions.

This review discusses inflammatory markers and therapeutic options in primary dysmenorrhea, focusing on prostaglandins, cytokines, and vasopressin, and evaluates treatments like NSAIDs, acupuncture, and physiotherapy.

This metabolomics study identifies ten urinary biomarkers linked to primary dysmenorrhea, providing insights into the metabolic disruptions that contribute to PD and suggesting potential new therapeutic targets.

This study links dysmenorrhea symptom phenotypes with distinct vaginal microbiome compositions, suggesting that microbiome imbalances contribute to more severe menstrual pain, which could be targeted in new treatments.

This systematic review highlights the significant association between primary dysmenorrhea and depression, emphasizing the need for integrated care that addresses both physical and mental health in affected women.

A bibliometric analysis of dysmenorrhea research from 1992 to 2022 reveals increasing global interest in its pathogenesis, treatment, and functional connectivity. It emphasizes the role of prostaglandins, nonsteroidal anti-inflammatory drugs, and traditional Chinese medicine in managing the condition.

Primary dysmenorrhea is a common and impactful condition affecting young women. This review explores its pathophysiology, symptoms, and treatment options to improve diagnosis and management in clinical practice.

Primary dysmenorrhea is a common, underdiagnosed condition that causes significant pain and affects women’s daily lives. The study highlights its pathophysiology, diagnostic approach, treatment options, and the need for greater awareness and research into its management.

This study examined the interaction between the vaginal microbiota and mycobiota in patients with vulvovaginal candidiasis (VVC). The research focused on understanding the role of different Candida species, specifically Candida albicans and Candida glabrata, in the pathology of VVC, and how they influence the vaginal bacteriome. The study aimed to identify the […]

This study investigates the link between gut microbiota and postpartum depressive disorder (PPD), identifying specific microbiota changes that correlate with depressive symptoms and hormonal levels. These findings could provide biomarkers for diagnosing and treating PPD.

This study explores the differences in microbiomes across breast tissue, oral, and urinary sites in women with and without breast cancer. Key findings suggest distinct microbiomic patterns in cancerous tissue and the urinary microbiome, providing new insights into the role of microbiota in cancer development.

This study examined the impact of estrogen on oral health and microbiome composition in COVID-19 patients, showing that postmenopausal women and men experience poorer oral health, which correlates with elevated proinflammatory cytokines and lower ACE2 expression, potentially influencing COVID-19 outcomes.

This study explores the impact of vaginal microbiota on IVF outcomes in women with infertility. It highlights how specific bacteria like Lactobacillus iners and Pseudomonas spp. can predict IVF success or failure, offering potential insights for personalized ART treatments.

This pilot study links gut microbiome diversity with breast cancer risk factors and tumor characteristics, particularly in HER2+ tumors and those with early menarche. It suggests microbial alterations in these groups that may influence cancer development and risk.

This study explores the vaginal microbiome and metabolome in women with common genital infections, revealing key microbial shifts and metabolic markers associated with infections like VVC, CT, and BV, highlighting potential diagnostic tools and therapeutic targets.

This study suggests that birth mode may influence the vaginal microbiota, with C-section delivery potentially linked to a less protective microbiome and higher odds of Molecular-BV in adulthood.

This study examined how bacterial vaginosis and HR-HPV infection influence vaginal microbiota diversity and cervical dysplasia in Chinese women, identifying Lactobacillus iners as a key microbial player in HPV-related CIN progression.

This study characterized the fungal communities in the female genital tract of young South African women and identified how fungal composition relates to bacterial vaginosis and other clinical factors.