Kimberly Eyer

This study identifies microbiome shifts in the lower genital tract of Chinese women with endometriosis, marked by Atopobium enrichment and changes in ribosome biogenesis and immune modulation. Findings suggest potential non-invasive biomarkers and therapeutic targets for endometriosis and adenomyosis.

This study identifies gut microbiota and metabolomic shifts in endometriosis, with altered bile acid biosynthesis and ALA metabolism. Elevated CDCA and UDCA levels, coupled with microbial changes, suggest potential biomarkers and therapeutic targets for managing inflammation in endometriosis.

This study reveals a distinct microbiome profile in deep endometriosis, with unique bacterial communities in lesion sites, suggesting a role in inflammation and disease progression. Potentially pathogenic genera like Pseudomonas and Alishewanella were abundant, highlighting their possible involvement in endometriotic lesion maintenance and inflammatory responses.

This study identifies the vaginal microbiome as a predictor of endometriosis severity, highlighting microbial shifts that correlate with rASRM staging. Anaerococcus emerged as a key biomarker for advanced disease stages, while CST IV dominance during menstruation suggests inflammatory shifts. Findings support the potential of non-invasive microbiome-based diagnosis for endometriosis.

This study reveals that diarrhea-predominant IBS (D-IBS) is linked to reduced microbial diversity and niche-specific dysbiosis in the gut.

This study reveals that IBS patients have significantly lower bifidobacteria counts in both fecal and duodenal samples compared to healthy controls. The marked reduction in Bifidobacterium catenulatum levels suggests a critical link to gut dysbiosis, impaired mucosal integrity, and potential contributions to symptom severity in IBS subtypes.

This study reveals that altered microbiota and elevated organic acids in IBS patients correlate with increased symptom severity, poorer quality of life, and heightened negative emotions. The findings suggest that microbial shifts leading to increased acetic and propionic acid production play a critical role in the pathophysiology of IBS.

This study identifies distinct microbiome signatures in pediatric IBS, revealing unique microbial imbalances linked to disease subtypes.

IBS-like symptoms in Parkinson’s disease are linked to distinct gut microbiota changes, particularly Prevotella depletion, implicating the microbiota-gut-brain axis in non-motor symptoms.

Müllerianosis theory posits that embryonic Müllerian duct remnants misplace and differentiate, forming endometrial-like tissues in non-uterine locations post-puberty, contributing to conditions like endometriosis.